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Because of the recent expiry of a large number of patents on the originator biological products, interest in the production and marketing of similar biotherapeutic products in Brazil has been increasing. The national producers have significant interest in this market and have been making a large amount of investments in these kinds of products. Since biotherapeutic products consume a large amount of the government health budget, the Brazilian government also has a big interest in thedoi:10.1016/j.biologicals.2011.06.021 pmid:21868247 fatcat:xp77na74anhmjdeynnzkfuijde