Genes that Delay Aging [chapter]

Helena M. Hinterding, Joris Deelen
2019 Encyclopedia of Gerontology and Population Aging  
Synonyms Age-related genes; Longevity genes; Longevityrelated genes Definition Genes that delay aging are genes that have shown to be associated with lifespan and/or longevity in animal models and/or humans when altered (e.g., overexpressed or knocked down). Overview Aging is to a minor, yet significant, extent genetically determined. Moreover, the genetic component of aging appears, at least partially, to be evolutionary conserved across species. Hence, to unravel this genetic component,
more » ... ch in model organisms, i.e., yeast (Saccharomyces cerevisiae), worms (Caenorhabditis elegans), fruit flies (Drosophila melanogaster), © Springer Nature Switzerland AG 2020 D. Gu, M. E. Dupre (eds.), Encyclopedia of Gerontology and Population Aging, https://doi.
doi:10.1007/978-3-319-69892-2_727-1 fatcat:we6orib76ff5jdkms5no7ltquq