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Sex-dependent change in the reactivity of isolated pulmonary arteries of gonadectomized rats under the intermittent hypoxia of different degree
2021
Regional blood circulation and microcirculation
Introduction. Pulmonary vasoconstriction is one of factors of hypoxic pulmonary hypertension (HPH). The progression of this disease depends on the degree of hypoxiа and seх. The aim of this study was to investigate the reactivity of isolated pulmonary vessels of male and female rats with HPH to vasoactive factors. Materials and methods. The experiments were on male and female of Wistar rats 190–200 g, which were gonadectomized. All animals were divided into 4 groups. One group of males and
doi:10.24884/1682-6655-2021-20-3-77-83
fatcat:xn457r6wa5c7xa2l52i4h7id7i