Autophagin-3 (ATG4C) is differentially expressed in the brains of patients with Parkinson's Disease [post]

Shahan Mamoor
2020 unpublished
Parkinson's Disease (PD) is characterized by loss of dopaminergic neurons in the substantia nigra of the basal ganglia (1). We mined published microarray datasets (2, 3) to identify genes whose expression was most different in the substantial nigra of patients with PD as compared to that of non-affected patients. We identified significant changes in expression of the gene encoding autophagin-3 (ATG4C) in the substantia nigra of patients with PD.
doi:10.31219/osf.io/6p529 fatcat:gikse3t56vgpnk6ukn4nke6ohy