Original Research Article The endothelium has emerged as the key regulator of vascular homeostasis, in that it has not merely a barrier function but also acts as an active signal transducer for circulating influences that modify the vessel wall phenotype. It has been demonstrated that Dietary patterns may induce a significant impact on vascular reactivity and endothelial function. Different studies demonstrated that healthy dietary lifestyle had a direct effect on the endothelial vascular

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... ons and reduce cardiovascular events (3). However, there is no study that shows clearly the effect of Fasting during Ramadan. The present review exposes the role of flow-mediated dilatation (FMD), most widely used non-invasive ultrasound to assess the effect of fasting during Ramadan in endothelial function and the improvement of cardiovascular functions.