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FORMULATION DESIGN AND EVALUATION STUDIES OF ESOMEPRAZOLE MAGNESIUM TRIHYDRATE ENTERIC COATED DUODENAL DRUG DELIVERY SYSTEM
Journal of Applied Pharmacy
Esomeprazole magnesium trihydrate tablets were formulated by directly compression and enteric coated with Acryl EZE. The rheological characteristics of powder beds were freely flowable and easily compressible. The Compressional parameters after enteric coating were found to be uniform and consistent. The hardness (Kg/cm2) was found in the range of 4.133±0.321 to 4.833±0.153. The enteric coated tablets were not disintegrated in simulated gastric fluid. The drug content in all formulations wasdoi:10.21065/19204159.3.234 fatcat:tzqzc6bqczgxvma27hadzdkgu4