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Lipopolysaccharide Induction of Cyclooxygenase-2 in Long-term Nasal Epithelial Cultures in Cystic Fibrosis
Archives of Otolaryngology - Head and Neck Surgery
Objective: To evaluate the lipopolysaccharide induction of cyclooxygenase-2 (COX-2) in long-term epithelial cultures from nasal polyp tissue of patients with cystic fibrosis (CF) and severe nasal polyposis. Design: Experimental and histologic study. Setting: Participants: Nasal polyp tissue was evaluated from 9 patients with CF and obstructing nasal polyps undergoing elective sinus surgery. Nasal mucosa from the hypertrophic inferior turbinate of 9 patients without a history of CF or aspirindoi:10.1001/archoto.2010.28 pmid:20403848 fatcat:4s6qnw3mtja7dgod3j6owkfiga