Trifluoromethylation of isonicotinic acid hydrazide has been investigated in trifluoroacetic acid containing pyridine, triethylamine and sodium trifluoroacetate dissolved in acetonitrile on platinum and glassy carbon electrodes using cyclic voltammetry. LSVs for isonicotinic acid hydrazide in 0.1 M TFA/ Py/TEA/NaTFA in acetonitrile on platinum electrode show that there is no distinct oxidation peak for the oxidation of isonicotinicacid hydrazide within the voltammetric region of 0.0 to 1.6 V vs

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... Ag and it gets oxidized anodically in the gas evolution region itself. TFA/ NaTFA medium shows slightly higher current density than the other two media for the oxidation of isonicotinic acid hydrazide. CVs for different concentrations of isonicotinic acid hydrazide show that anodic peak becomes broad and flat. It shows that severe adsorption of INAH/product takes place on the glassy carbon electrode during the voltammetry scanning. Galvanostatic electrolysis of INAH in TFA/Py/ACN medium at low current density on Pt shows good conversion with low selectivity.