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Obligatory Amino Acid Exchange via Systems bo,+-like and y+L-like
1996
Journal of Biological Chemistry
Mutations in the rBAT gene cause type I cystinuria, a common inherited aminoaciduria of cystine and dibasic amino acids due to their defective renal and intestinal reabsorption (Calonge, M. A. 92, 9667-9671). One important question that remains to be clarified is how the apparently non-concentrative system b o,؉ -like, associated with rBAT expression, participates in the active renal reabsorption of these amino acids. Several studies have demonstrated exchange of amino acids induced by rBAT in
doi:10.1074/jbc.271.30.17761
pmid:8663357
fatcat:3o7ze2iuord27nkmjouytktgpm