Molecular Characterization of Carbapenem-Resistant Acinetobacter baumannii Clinical Isolates from Egyptian Patients [article]

Reem M Hassan, Sherifa T Salem, Saly Ismail Mostafa Hassan, Asmaa Sayed Hegab, Yasmine S Elkholy, Reem M Hassan, Sherifa T Salem, Saly Ismail Mostafa Hassan, Yasmine S Elkholy
2020 bioRxiv   pre-print
Author summary Carbapenem-resistant A. baumannii has become a real global health threat. The aim of the present study was to characterize and to assess the prevalence of carbapenemases among 206 CR-AB clinical isolates from Egyptian patients. We concluded that the most prevalent type of ß-lactamases genes among CR-AB isolates collected from Egyptian patients were blaOXA-23 followed by blaNDM-1 and blaKPC. In this study, IS Aba1 was detected upstream 10% of blaOXA-23 positive isolates only which
more » ... indicates that the spread of resistance among Acinetobacter isolates could be either chromosomal or plamid- mediated.
doi:10.1101/2020.08.24.264911 fatcat:p5wa6nl5q5ci5mvj6hgbr3bi4i