A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2019; you can also visit the original URL.
The file type is
Atorvastatin attenuates atrial structural, autonomic and electrophysiologic remodelling by its anti-oxidant and anti-inflammatory action in atrial fibrillation dogs
Purpose The protective effects of statins against atrial fi brillation (AF) have been observed in many clinical trials but the underlying mechanisms remain unclear. Therefore we investigated the role of atorvastatin on atrial remodelling in AF dogs and explored the potential mechanism. Methods Three groups of dogs were used: sham-operated, AF and atorvastatin. Dogs in the AF and atorvastatin groups underwent 6-week atrial pacing. Atorvastatin was administered 1 week before and during thedoi:10.1136/heartjnl-2011-300867.17 fatcat:yy25dmgjmnfa5fgieuc6b6bta4