Microwave-assisted synthesis and regioisomeric structural elucidation of novel benzimidazo[1,2d][1,4]benzodiazepinone derivatives

2009 ARKIVOC  
The synthesis of 5H-benzimidazo [1,2-d] [1,4] benzodiazepin -6(7H)-ones 3a-e from readily available 2-(2-aminophenyl)-1H-benzo[d]imidazole derivatives 2a-e and 2-bromoacetyl bromide under microwave conditions is described. Unambiguous structural elucidation of the obtained regioisomers was finally established by means of 2D-NOESY experiment.
doi:10.3998/ark.5550190.0010.c11 fatcat:g3kvueiscbh3bnqohf4az772sy