Transport of a Brownian particle with an oscillating radius freely diusing in an asymmetric corrugated channel was simulated over a range of driving forces for a series of temperatures and angular frequencies of radial oscillation. It was observed that there was a strong inuence of self-oscillation frequency on the average particle velocity. This eect can be used to control rectication of biologically active particles as well as for their separation according to their activity, for instance in the separation of living and dead cells.