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A Proliferation-Inducing Ligand Regulation in Polymorphonuclear Neutrophils by Panax ginseng
Archivum Immunologiae et Therapiae Experimentalis
A proliferation-inducing ligand (APRIL) is a member of the tumor necrosis factor superfamily that was first identified as a factor favoring tumorigenesis. APRIL is important fitness and survival factors for B cells and plasma cells in the periphery. Considering this, as well as the quantitative predominance of neutrophils among the peripheral blood leukocytes, we carried out the first study assessing the influence of the transforming growth factor (TGF)-β signaling pathway on APRIL expressiondoi:10.1007/s00005-020-00597-z pmid:33125603 fatcat:skq2oub6r5hcjmyslgkzpdnv3u