Neurostimulation for Conlrol of Phantom Limb Pain : Spinal Cord, Thalamus and Cerebral Cortex
幻肢痛に対する神経(脊髄,視床,大脳皮質)刺激療法 : 新しい仮説と将来の展望

Yoichi Katayama, Masahiko Kasai
2003 Japanese Journal of Neurosurgery  
In patients with phantom limb , the primary somatosensory cortex may undergo reorganizatioD of receptive field representation ( invasion of the phant〔,m limb area by the adjacent area ) . It has been rep 〔 レ rted that this reor − ganization is highly correlated with phantom limb pain and unrelated to the non − painful phantom sensation . These findings led to t : he hypothesis that restoration of the original cortical organization might diminish phantom limb pain . Similar reorganization of
more » ... ptive field representation within the thalamic sensory relay nucleus has been shown by microrecordings and m { crostimulation during surgery for therapeutic electrode implantatiol 】 , We review the published data and our own experience regarding the ef 〔 ects of neurostimulation therapies on phantom limb pain( spinal cord , thalamic sensory relay nucleus and motor cortex )仕om a view point that neurostimulation thera − pies produce their effects through restoration of the original receptive 丘eld organization by artificial input to the representation of the phantoml limb area . Many phenomena observed during neurostimulation therapies are better explained by such a hypothesis rather than classic gate control theory.
doi:10.7887/jcns.12.395 fatcat:ttgzwgt7n5axlhzy57umrgaoqu