Chromophobe renal cell carcinoma〔 Ch − RCC)and collecting duct carcinoma ( CDC〕are derived from the collecting duc 亡epithelia . Herein is presented a case ofRCC possessingthechromophobe RCC and CDC elements occurringin a64 yeur − o↓ d Japa 皿 ese womun 、 The putient wus referred to our hospitai with comphints ofpersistentback pain andfever , Rudiologic examinations revealed aleft renal tumor , and radical nephrectomy was performed , The patient died with multiple metastases , S months afl / er

more »

... e operation , The reseeted tumor showedan invasive grewth, and its cut surfacewas heterogeneus with hemor ・ rhage and necrosis . Histologically , the tumor was composed of Ch − RCC ele . ment with dedifferentiation , and CDC elements 、 The Ch − RCC and CDC ele・ ments had obvious histologica ! transition , Lectin histochemistry and immuno ・ histochemistry confirmed that this tumor was derived from the distaL neph − ron、 c − KIT , p53 and Ki67 antigen showed differential localiZation between the