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FLINO-A new method for immunofluorescence bioimage normalization
2021
Bioinformatics
Multiplexed immunofluorescence bioimaging of single-cells and their spatial organization in tissue holds great promise to the development of future precision diagnostics and therapeutics. Current multiplexing pipelines typically involve multiple rounds of immunofluorescence staining across multiple tissue slides. This introduces experimental batch effects that can hide underlying biological signal. It is important to have robust algorithms that can correct for the batch effects while not
doi:10.1093/bioinformatics/btab686
pmid:34601553
pmcid:PMC8723144
fatcat:vvpegndhmzgblh7taa33furkzi