Dilutional Hyponatremia in Patients With Cirrhosis and Ascites

Almudena Porcel, Fernando Díaz, Paloma Rendón, Manuel Macías, Leopoldo Martín-Herrera, José A. Girón-González
2002 Archives of Internal Medicine  
Objectives: To analyze the predisposing factors, modifications of vasoactive systems, and prognosis of patients with cirrhosis and hyponatremia. Patients and Methods: Fifty-four patients with hyponatremia (serum sodium level of Ͻ130 mEq/L after 5 days of hyponatremic diet and no diuretic therapy). Twenty cirrhotic patients served as controls. We measured plasma renin activity and levels of plasma aldosterone, norepinephrine, and antidiuretic hormone. Follow-up identified the development of
more » ... orenal syndrome and death. (REPRINTED) ARCH INTERN MED/ VOL 162, FEB 11, 2002 WWW.ARCHINTERNMED.COM 323
doi:10.1001/archinte.162.3.323 pmid:11822925 fatcat:2mamrd2dl5bwvpg4j3mmw6jz74