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Much remains unknown about the progression and heterogeneity of mutational processes in different cancers and their diagnostic and clinical potential. A growing body of evidence supports mutation rate dependence on the local DNA sequence context for various types of mutations. We propose several tools for the analysis of cancer context-dependent mutations, which are implemented in an online computational framework MutaGene. The framework explores DNA context-dependent mutational patterns anddoi:10.1093/nar/gkx367 pmid:28472504 pmcid:PMC5793731 fatcat:zrliuqo4l5godawceqfhsfqfyu