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Perivascular smooth muscle -actin is reduced in the endometrium of women with progestin-only contraceptive breakthrough bleeding
It has been shown that the endometrium of women using progestin-only contraceptives has increased vascular fragility, although the structural basis for this weakness is unknown, as is its role in breakthrough bleeding (BTB). Perivascular cells such as pericytes and vascular smooth muscle cells surround capillaries during the maturation process following angiogenesis, and act to strengthen and stabilize the vessels. The aim of the present study was to quantify endometrial perivascular smoothdoi:10.1093/humrep/15.suppl_3.78 pmid:11041224 fatcat:f6l4pigyr5dplgybzfgqa27t64