Incidence of Vitamin D Deficiency in Children in Babylon Province
Indian Journal of Public Health Research & Development
Purposes of Study: analysis and measurement of incidence and to show clinical factors that association vitamin D deficiency in children between < 1 year -11 years old. Design and Method: This study is prospective, total children 172 with 108 male and 64 female. Age group of children extend from <1-11 years old and planned into four groups: < 1, 1-3, 4-7, 8-11 years old. Serum 25-OHD assay, serum calcium and alkaline phosphatase were measured. Vitamin D deficiency were arrange into three groups
... into three groups according to severity of vitamin D as following : mild vitamin D deficiency is 20-30 ng/ml, moderate vitamin D deficiency is 10-20 ng/ml and severe vitamin D deficiency is< 10 ng/ml. Results: Among 172 children, 95 of children were healthy, 77 children had vitamin D deficiency. 25-OHD deficiency showed 16.8%, 38.9% and 44.2% in mild, moderate and severe cases respectively. Age of children was older age (5.59±3.42) in vitamin D deficiency. Mean vitamin D deficiency is much lower with highly significant association (P value = 0.00) in compare to normal children. Male gender were predominant in normal and deficient vitamin D respectively but with independence association. Serum calcium and alkaline phosphatase measurement showed hypocalcaemia with elevated level of alkaline phosphatase in vitamin D deficiency and both of them had highly significant difference (P value = 0.00). Conclusion: Vitamin D deficiency is very common (44.76%) in age group between <1-11 years old and severe vitamin D deficiency (< 10 ng/ml) is the commonest vitamin D deficiency (44.2%) specially older age group (8-11years). vitamin D deficiency is associated with significant hypocalcaemia and elevated alkaline phosphatase.