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Morphometric Analysis of Arteriolar Tortuosity in Human Cerebral White Matter of Preterm, Young, and Aged Subjects
2007
Journal of Neuropathology and Experimental Neurology
Arteriolar tortuousities, consisting of vascular coils, loops, and spirals, appear in white matter in a subset of human cerebral vessels. Computerized morphometry was used to analyze brain sections from a broad age range of subjects to determine whether tortuosity is a phenomenon of aging or is associated with leukoaraiosis (LA) or Alzheimer disease (AD). Autopsy brains were studied from 55 subjects ranging in age from 23 weeks postconception to 102 years. Fourteen aged subjects were diagnosed
doi:10.1097/nen.0b013e3180537147
pmid:17483690
fatcat:pu2qlnaoq5f6bas7z4pbmfp3aq