Explicit motor sequence learning with the paretic arm after stroke

Melanie K. Fleming, Di J. Newham, John C. Rothwell
2016 Disability and Rehabilitation  
Ph. +44 (0) 207 848 6679 Fax: +44 (0) 207 848 6325 Word count: 3703 Explicit motor sequence learning with the paretic arm after stroke Abstract Purpose: Motor sequence learning is important for stroke recovery, but experimental tasks require dexterous movements, which are impossible for people with upper limb impairment. This makes it difficult to draw conclusions about the impact of stroke on learning motor sequences. We aimed to test a paradigm requiring gross arm movements to determine
more » ... r stroke survivors with upper limb impairment were capable of learning a movement sequence as effectively as age-matched controls. Materials and Methods: In this case-control study, 12 stroke survivors (10-138 months post-stroke, mean age 64 years) attempted the task once using their affected arm. Ten healthy controls (mean 66 years) used their non-dominant arm. A sequence of 10 movements was repeated 25 times. The variables were: time from target illumination until the cursor left the central square (onset time; OT), accuracy (path length) and movement speed. Results: OT reduced with training (p<0.05) for both groups, with no change in movement speed or accuracy (p>0.1). We quantified learning as the OT difference between the end of training and a random sequence; this was smaller for stroke survivors than controls (p=0.015). Conclusions: Stroke survivors can learn a movement sequence with their paretic arm, but demonstrate impairments in sequence specific learning.
doi:10.1080/09638288.2016.1258091 pmid:27927022 fatcat:vmpbvwziv5exzjy2q7u3r5vxlu