Experimental Infection of Recent Field Isolates of Feline Herpesvirus Type 1

Masataka HAMANO, Ken MAEDA, Fuminori MIZUKOSHI, Yumi UNE, Masami MOCHIZUKI, Yukinobu TOHYA, Hiroomi AKASHI, Kazushige KAI
2003 Journal of Veterinary Medical Science  
Two field isolates of feline herpesvirus type 1 (FHV-1) designated as 00-015 and 00-035, were obtained from cats diagnosed as feline viral rhinotracheitis (FVR) in Japan. To analyze the character of recent FHV-1, these two isolates and our laboratory strain C7301 were inoculated experimentally to specific-pathogen-free cats. Although all cats showed typical FVR symptoms, more severe clinical symptoms were observed on cats infected with the isolates 00-015 and 00-035 compared with those of
more » ... infected cats. Severe ocular lesions including conjunctivitis were found in the cats infected with the isolates, indicating that the recent FHV-1 has a potential to induce severe FVR symptoms including ocular lesions. KEY WORDS: conjunctivitis, feline herpesvirus type 1, feline viral rhinotracheitis.
doi:10.1292/jvms.65.939 pmid:12951431 fatcat:2vnepdcaszf7jo6ogkzajtckvu