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The many faces of CD4+ T cells: Immunological and structural characteristics
© 2020 by the authors. Licensee MDPI, Basel, Switzerland. As a major arm of the cellular immune response, CD4+ T cells are important in the control and clearance of infections. Primarily described as helpers, CD4+ T cells play an integral role in the development and activation of B cells and CD8+ T cells. CD4+ T cells are incredibly heterogeneous, and can be divided into six main lineages based on distinct profiles, namely T helper 1, 2, 17 and 22 (Th1, Th2, Th17, Th22), regulatory T cellsdoi:10.26181/6024c4de25020 fatcat:ovoy3frp5nhqdfgu4uviadpify