COBREXA.jl: constraint-based reconstruction and exascale analysis [article]

Miroslav Kratochvil, Laurent Heirendt, St. Elmo Wilken, Taneli Pusa, Sylvain Arreckx, Alberto Noronha, Marvin van Aalst, Venkata P. Satagopam, Oliver Ebenhoeh, Reinhard Schneider, Christophe Trefois, Wei Gu
<span title="2021-06-07">2021</span> <i title="Cold Spring Harbor Laboratory"> bioRxiv </i> &nbsp; <span class="release-stage" >pre-print</span>
COBREXA.jl is a Julia package for scalable, high-performance constraint-based reconstruction and analysis of very large-scale biological models. Its primary purpose is to facilitate the integration of modern high performance computing environments with the processing and analysis of large-scale metabolic models of challenging complexity. We report the architecture of the package, and demonstrate its scalability by benchmarking the task distribution overhead incurred when performing analyses of
more &raquo; ... any variants of multi-organism community models simultaneously.
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