A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2021; you can also visit the original URL.
The file type is
Adoptively Transferable Tolerance Induced by CD45RB Monoclonal Antibody
Journal of the American Society of Nephrology
Abstract. The phenomenon of rejection remains the most serious problem in transplantation. The ultimate goal in transplant immunology is to develop therapeutic strategies that lead to tolerance. It has been shown that two injections of a monoclonal antibody to CD45RB leads to indefinite acceptance of renal allografts in mice. Moreover, the CD45RB monoclonal antibody reverses acute rejection and still induces tolerance. The purpose of this study was to assess mechanisms that could underlie thisdoi:10.1681/asn.v102374 fatcat:jb4fi5l5zzcrbj47exh5eqe6d4