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Association of Genetic Polymorphism of Insulin Receptor Substrate 1 (IRS-1) with Polycystic Ovary Syndrome Pathogenicity in Iraqi Women
2021
Medico-Legal Update
Insulin receptor substrate 1 (IRS-1) is an intracellular signaling adapter protein that integrates and coordinates multiple biologically key extracellular signals within the cell, is also a key central receptor in insulin signaling, and plays a focal role in maintaining essential cellular capabilities, e.g., survival, development and digestion system. IRS1 is essentially found in the cytoplasm But localization in nucleus may occur in some cell types and under certain stimuli. Materials and
doi:10.37506/mlu.v21i2.2699
fatcat:5fbnw2vf5naqdjbknpbzeznxbq