Low Density Lipoprotein [chapter]

Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine  
We have reported the use of a retroviral vector to introduce the low density lipoprotein (LDL) receptor gene into receptor-deficient Watanabe heritable hyperlipidemic (WHHL) rabbit fibroblasts (Miyanohara, A., M. E Sharkey, D. Steinberg, J. L. Witztum, and T. Friedmann. 1988. Pmc. Natl. Acad. Sci. Abbreviations: LDL, low density lipoprotein; WHHL, Watanabe heritable hyperlipidemic rabbit; FH, familial hypercholesterolemia; CHO, Chinese hamster ovary; HMG-CoA, 3-hydroxy-3-methylglutaryl coenzyme
more » ... A; LTR, long terminal repeat; LDS, lipoprotein-deficient serum; FCS, fetal calf serum; RSV, Rous sarcoma virus; SV40, simian virus 40; h-LDL-R, human LDL receptor; luc, luciferase; &gal, 0galactosidase; Neo, Tn5 neomycin-resistance; DHFR, dihydrofolate reductase.
doi:10.1007/3-540-29623-9_7691 fatcat:s6lopuogjfcspkyhcaouzpayxq