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Etiology and Morphogenesis of Congenital Heart Disease
For decades, it has been recognized that proteins, which are encoded by our genomes via transcription and translation, are building blocks that play vital roles in almost all biological processes. Mutations identified in many proteincoding genes are linked to various human diseases. However, this "proteincentered" dogma has been challenged in recent years with the discovery that majority of our genome is "noncoding" yet transcribed. Noncoding RNA has become the focus of "next generation"doi:10.1007/978-4-431-54628-3_44 fatcat:5qaehnqhubhr5mk3qgmns5dpca