Skin photoageing: mechanisms of development and particular features of clinical manifestations

A. A. Kubanov, M. B. Zhilova, A. A. Kubanova
2017 Vestnik Dermatologii i Venerologii  
The article discloses current concepts of mechanisms of development of skin photoageing caused by UV irradiation (UVA and UVB). Chronic exposure of skin to UV irradiation results in damage of genome DNA, development of DNA mutations, damage of proteins, membrane lipids, collagen and yellow fibers, degradation of the intercellular substance of the skin, development of a chronic inflammation, immunosuppression, melanogenesis disorders and increased angiogenesis. The authors described major
more » ... l manifestations of skin photoageing and their histological characteristics.
doi:10.25208/0042-4609-2014-0-5-53-59 doaj:48dc61501b4940f3997ef4b8ffa58a01 fatcat:xsrgoyi3dnb7nc5rvsdzfmjrt4