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Spidey: A Tool for mRNA-to-Genomic Alignments
2001
Genome Research
We have developed a computer program that aligns spliced sequences to genomic sequences, using local alignment algorithms and heuristics to put together a global spliced alignment. Spidey can produce reliable alignments quickly, even when confronted with noise from alternative splicing, polymorphisms, sequencing errors, or evolutionary divergence. We show how Spidey was used to align reference sequences to known genomic sequences and then to the draft human genome, to align mRNAs to gene
doi:10.1101/gr.195301
pmid:11691860
pmcid:PMC311166
fatcat:ibsx3vkkc5g7bjdwp6ovrnysxq