To determine the exposure rates of the risk factors and the distribution characteristics of the population at high risk for stroke in Zunyi City, and thereby provide references for health management of the population. Cluster sampling was applied to collect the medical histories, laboratory tests, and physical examinations of permanent residents in Zunyi City, Guizhou Province, for the purpose of analyzing the characteristics of risk factors in the population at high risk for stroke. A total of

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... 1,382 residents were screened as the high-risk population [681 males (49.3%), 701 females (50.7%)] with a detection rate of 11.11%. For the high-risk population, the top 5 risk factors for stroke were hypertension (78.9%), dyslipidemia (64.5%), obesity (54.1%), lack of exercise (48.8%), and smoking (35.1%). The exposure rates of females at high risk of hypertension, diabetes, dyslipidemia, and obesity were significantly higher than those of males, while the smoking rate of the high-risk males was significantly higher than that of the females. Significantly different exposure rates of stroke from hypertension, smoking, dyslipidemia, lack of exercise, overweight or obesity, and family history were shown in high-risk populations of different ages, while the incidence of stroke/transient ischemic attack (TIA) showed an increasing trend with aging. Hypertension, dyslipidemia, and obesity are the main risk factors for stroke in Zunyi City, with the detection rate of high-risk females being slightly higher than that of the males, and the population with a history of stroke/TIA performed better than the population with more than 3 risk factors.