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Several ideas for solving the problem of fermion mass hierarchy and mixing and specific supersymmetric models that realize it are reviewed. In particular, we discuss many models based on SO(10) in four dimensions combined with a family symmetry to accommodate fermion mass hierarchy and mixing, including the case of neutrinos. These models are compared and various tests that can be used to distinguish these models are suggested. We also include a discussion of a few SO(10) models in higherdoi:10.1142/s0217751x03017026 fatcat:pu57gqsayjacljnqwguj4tsel4