GİRİŞ Adenotonsillektomi kulak burun boğaz (KBB) alanında çocukluk döneminde en sık yapılan ameliyatlar-dan biridir. Bu endikasyonların birçoğunun doğrudan veya başka sistem etkileri ile çocuğun büyümesi üzerinde olumsuz etkileri bulunmaktadır. Adenotonsillektomi operasyonlarının çocuğun büyümesi üzerin-aBSTraCT Although, in practice it has been believed that linear growth, and weight of the children who underwent adenotonsillectomy increase, however this presumption has not been proved by

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... ate number of studies performed using objective parametres. The aim of this study is to determine the effect of adenotonsillectomy upon growth and growth biomarkers. in a tertiary care hospital. Twenty-eight prepubertal children including 20 boys and 8 girls participated in our study. The mean age at surgery was 6.78±2.58 years (range 4-13 years). Weight and height measurements of all subjects, and also IGF-1 and IGFBP-3 serum levels with standard deviation scores were evaluated before and 1-6 months after adenotonsillectomy. Serum levels of IGF-1 and IGFBP-3 were significantly higher at 1 month and 6 months after adenotonsillectomy compared to preoperative levels (p<0.001). Also Serum levels of IGF-1 and IGFBP-3 were significantly higher at postoperative 6 months compared to at postoperative 1 month (p<0.001). A positive correlation detected between the rise of serum levels of IGF-1 and IGFBP-3, and the weight gain and linear growth in all of the 28 patients who were included in this study. A positive correlation was demonstrated between increments in weight and length and IGF-1 and IGFBP-3 serum.