Objectives: Prognostic parameters in stroke management are important for emergency department physicians to reduce mortality and morbidity. No parameters could be determined for prognosis in acute stroke. In this study, we aimed to determine whether serum procalcitonin (PCT), lactate and HgA1c levels at admission and changes of PCT and lactate levels in 2 hours were associated with short-term functional outcome (3rd day) after acute ischemic stroke. Materials and Methods: This was a prospective

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... observational prognostic test study. All consecutive patients admitted to the emergency department and diagnosed as the first episode of acute ischemic stroke were included in the study. On admission and 2nd hour, PCT and lactate levels and admission HgA1c levels were collected from all subjects. Our primary aim was to correlate these values with the Modified Rankin Scale (mRS) which shows the functional outcome. Our secondary aim was determining correlation with mortality on the 3rd day and to determine their predictive value. Results: There was no statistically significant difference between the favorable (mRS <2) and non-favorable groups in terms of PCT and lactate values and PCT and lactate clearances. There was a statistically significant difference between the two groups in terms of HgA1c value. When the threshold value analysis was performed to determine the non-favorable outcome, the threshold value was determined as 5.7. Conclusion: Our results demonstrate that ischemic stroke patients with higher levels of HgA1c at the time of initial presentation have an increased risk for poor functional neurological outcome (high mRS) on the 3rd day. We couldn't analyze mortality due to the low patient number.