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LINC00319 acts as a microRNA-335-5p sponge to accelerate tumor growth and metastasis in gastric cancer by up-regulating ADCY3
American Journal of Physiology - Gastrointestinal and Liver Physiology
Gastric cancer (GC) is one of the most common cancers in the world and remains a heavy burden of health worldwide. Adenylate cyclase 3 ( ADCY3) is a widely expressed membrane-associated protein in human tissues and has been identified to be a new molecular target of GC. Long non-coding RNAs (lncRNAs) have substantial influence on tumorigenesis and progression of tumors by binding to microRNAs (miRNAs). Therefore, this study is to clarify the mechanism by which LINC00319 sponges miR-335-5p todoi:10.1152/ajpgi.00405.2018 pmid:31433213 fatcat:txxuox3ksba2hngy7ldhcjbgaq