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Granulocyte colony-stimulating factor (G-CSF) levels in serum were determined by a highly-sensitive chemiluminescent enzyme immunoassay (limit of detection, 0.5 pg/ml) in 54 patients with Graves' disease including 6 patients complicated with methimazole-induced agranulocytosis. Serum G-CSF levels in patients with Graves' disease were not different from normal subjects and did not correlate with serum FT 4 level or circulating neutrophil counts. Before the onset of agranulocytosis, there was nodoi:10.1507/endocrj.51.579 pmid:15644577 fatcat:qozarcl5szbprphh3uonmvlqeq