Shirashool can be clinically correlated with the Migraine; which is commonly occurring vascular headache. It presents cardinal symptom of pain on one half of the head. Factors which trigger the disease include weather, missing a meal, stress, alcohol and certain types of food items. About 50% of women reported menstrual periods as a significant trigger. Additionally, allergic reactions, exposure to loud noises or certain odors, smoking, or long exposures to computer screens/televisions could

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... d to Migraine attacks. PresentClinical study of Dologran Tablets with respect to Shirashool(Migraine) was conducted on 30 patients irrespective of sex in the age group of 18 to 60 yrs. All the patients presented with classical features of Shriashool. The present study also includes a causation of the disease and clinical conditions considered for differential diagnosis of Shirashool found in classical texts. Dologran Tablet was administered with warm water for 30 days. Appropriate diet was advised to all the patients. Follow up was planned every 15 days till 1 month to assess if there is any recurrence of symptoms.Highly significant results were observed and improvement in cardinal symptoms of Shirashool was observed. Dologran Tablets appears to provide good clinical improvement in patients with Shirashool.