Coherent diffraction of a single virus particle: The impact of a water layer on the available orientational information

F. Wang, E. Weckert, B. Ziaja, D. S. D. Larsson, D. van der Spoel
2011 Physical Review E  
Coherent diffractive imaging using x-ray free-electron lasers (XFELs) may provide a unique opportunity for high-resolution structural analysis of single particles sprayed from an aqueous solution into the laser beam. As a result, diffraction images are measured from randomly oriented objects covered by a water layer. We analyze theoretically how the thickness of the covering water layer influences the structural and orientational information contained in the recorded diffraction images. This
more » ... dy has implications for planned experiments on single-particle imaging with XFELs.
doi:10.1103/physreve.83.031907 pmid:21517525 fatcat:jlyyditrdfhy3flchynjq7v3am