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Multiscale assay of unlabeled neurite dynamics using phase imaging with computational specificity (PICS)
[article]
2020
arXiv
pre-print
Primary neuronal cultures have been widely used to study neuronal morphology, neurophysiology, neurodegenerative processes, and molecular mechanism of synaptic plasticity underlying learning and memory. Yet, the unique behavioral properties of neurons make them challenging to study - with phenotypic differences expressed as subtle changes in neuronal arborization rather than easy to assay features such as cell count. The need to analyze morphology, growth, and intracellular transport has
arXiv:2008.00626v1
fatcat:sn5egveh5na3tefulgzscxjo3u