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Functional interaction of DYX1C1 with estrogen receptors suggests involvement of hormonal pathways in dyslexia
2009
Human Molecular Genetics
Dyslexia, or specific reading disability, is the unexpected failure in learning to read and write when intelligence and senses are normal. One of the susceptibility genes, DYX1C1, has been implicated in neuronal migration, but little is known about its interactions and functions. As DYX1C1 was suggested to interact with the U-box protein CHIP (Carboxy terminus of Hsc70-Interacting Protein), which also participate in the degradation of estrogen receptors alpha (ERα) and beta (ERβ), we
doi:10.1093/hmg/ddp215
pmid:19423554
fatcat:44543htdrrc6bbv2zoeb7w2zwy