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Gelatinases Increase in Bleomycin-induced Systemic Sclerosis Mouse Model
Iranian Journal of Allergy, Asthma and Immunology
Systemic sclerosis is a fibrotic autoimmune disease in which aberrant remodeling of the extracellular matrix in organs disturbs their functionalities. The aim of this study was to investigate the expression of gelatinases on systemic sclerosis. Consequently, a mouse model of systemic sclerosis was employed and the gelatinolytic activity of gelatinases was evaluated on the fibrotic tissues of this model. Two groups of ten mice were considered in this work: a group of systemic sclerosis model anddoi:10.18502/ijaai.v18i2.921 fatcat:oqjoxnw6y5g6zdalzpxcbdhuam