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MiniScrub: de novo long read scrubbing using approximate alignment and deep learning
[article]
2018
bioRxiv
pre-print
Long read sequencing technologies such as Oxford Nanopore can greatly decrease the complexity of de novo genome assembly and large structural variation identification. Currently Nanopore reads have high error rates, and the errors often cluster into low-quality segments within the reads. Many methods for resolving these errors require access to reference genomes, high-fidelity short reads, or reference genomes, which are often not available. De novo error correction modules are available, often
doi:10.1101/433573
fatcat:5xr56ko22vdh3obqqxjrgodkhm