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Abstract. The intracellular reproduction of M. tuberculosis in the cytoplasm of diploid cells was observed. In the cells under placental interferon (plaferon) protection cytopathic effect of mycobacteria as well as intracellular reproduction of the agent were depressed. Interferon stimulated the activity of the peritoneal cells of mice and depressed the reproduction of M. tuberculosis in the cytoplasm of macrophages. M. tuberculosis revealed slight interferonogenic activity in cell cultures.doi:10.5281/zenodo.5689427 fatcat:dfg6xzke7jbixn7jdvg5y7aqqa