Some points in the Physiology of Gland Nerves

J. Rose Bradford
1888 Journal of Physiology  
IN previous communications' it has been shown that excitation of the nerves of the salivary glands is accompanied by electrical changes which are opposite in sign, according as to whether the nerve excited contained in greater abundance so-called secretory or trophic fibres. The electrical change following the stimulation of the former fibres consists of a positive variation of the current of rest, whereas a negative variation is seen on stimiulation of the so-called trophic fibres of
more » ... . It was further shown that the former effect was closely connected with the flow of liquid through the gland cells and ducts, and that the latter effect was simiilarly related in all probability to the elaboration of the organic constituents of the saliva. These results were obtained fronm a comparison of the effects in different glands, i.e. the submaxillary and parotid glands of the cat and dog, under different conditiolns. From certain apparently anomalous resuilts, as, for instance, the occasional free secretion of parotid saliva on sympathetic secretion, it was felt that the difficult question of the nature of gland nerves was one that required further investigation. The present paper details the result of work which was of the nature of an attempt in this direction. This question of the nature of gland nerves is intimately connected with the vexed question of the origin of the paralytic secretion, and hence some experiments were carried out on the effects followiing the division of the gland nervez. The effects of section of the chorda, sympathetic etc. were observed on thirty cats and dogs, and in all cases full antiseptic precautions were taken to ensure healing by first intention. In the experiments detailed below on the results of nerve stimulation, the gland was, in the great majority of 1
doi:10.1113/jphysiol.1888.sp000289 pmid:16991491 fatcat:cctssaqwobc2hkcldrtrbhygnu