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The increasing availability of new agents to treat multiple sclerosis poses new challenges for clinicians who seek therapies that are both safe and effective for their patients. The introduction of additional effective therapies has been accompanied by the recognition of serious side effects. The clinician now must weigh both the benefits and risks of therapies to help patients decide which treatment best fits each patient's risk/benefit profile. An optimal selection of therapies relies on adoi:10.1016/j.msard.2014.05.003 pmid:25221744 pmcid:PMC4159169 fatcat:7unjhpvujzg7nffpfwmtohzuz4