Bio-adhesives play a pivotal role in a wide range of medical applications. However, there are some problems about their application in varied pH values and low adhesion force under wet conditions. Here, we report new recombinant fusion protein achieved by mussel foot proteins (Mfps) of Mytilus Californianus and gas vesicle protein A (GvpA) of Anabaena flos-aquae by genetic engineering methods. These chimeric proteins self-assembled into ß-sheet rich fibres because of GvpA amyloid structure.

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... , their adhesion forces were significantly increased especially in alkaline environment based on Mfp-3 and Mfp-5. This study illustrates that copolymer of Mfp-5-GvpA:GvpA-Mfp-3 can be used as an underwater sturdy adhesive with tolerance to auto-oxidation, especially at basic conditions.