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Objective: To measure serum tumor necrosis factor-alpha (TNF-α) and in Iraqi women with first trimester missed and threatened miscarriage and compare their levels with those of normal pregnancy. Methods: A case control study was conducted from , Iraq. Samples were obtained from 62 pregnant women in the first trimester: eighteen women with threatened miscarriage ( A and D (17.68±2.90 pg/ml., 9.75±1.66 pg/ml. and. 4.41±1.23 pg/ml., p=0.039 and p=0.0001 respectively). A significant decrease indoi:10.21608/besps.2011.35956 fatcat:kivpen46pve7toyff5j5nbrs44