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IN SILICO STUDIES OF DITERPENES EXTRACTED FROM Paubrasilia echinata Lam. AND DERIVATIVES AGAINST HIV-1 INTEGRASE AND REVERSE TRANSCRIPTASE
2022
Periódico Tchê Química
HIV, whose viral multiplication is associated with three enzymes. Reverse transcriptase is responsible for synthesizing vital DNA based on its RNA; integrase is responsible for integrating viral DNA into human DNA; and protease is responsible for cleaving the genetic code into smaller, functional units. Many research groups around the world are motivated by the proposal of a new bioactive against HIV. Objectives: To propose natural diterpenes or synthetic products from the Pau-Brasil plant
doi:10.52571/ptq.v19.n42.2022.05_messias_pgs_46_59.pdf
fatcat:hd4pvmjotjba5pobto7vltnbem